منابع مشابه
Three-component asymmetric catalytic Ugi reaction--concinnity from diversity by substrate-mediated catalyst assembly.
The first chiral catalyst for the three-component Ugi reaction was identified as a result of a screen of a large set of different BOROX catalysts. The BOROX catalysts were assembled in situ from a chiral biaryl ligand, an amine, water, BH3·SMe2, and an alcohol or phenol. The catalyst screen included 13 different ligands, 12 amines, and 47 alcohols or phenols. The optimal catalyst system (LAP 8-...
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Spiropyrrolidinyloxindole compounds are synthesized in moderate to excellent yield via a highly diastereoselective Cu(I)-catalysed three-component assembly reaction of an imine, diazo-compound and substituted olefin dipolarophile.
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Chlorination-elimination chemistry coupled with three-component Joullié-Ugi reaction and facile deprotection allowed efficient access to an array of polyhydroxylated pyrrolidines through parallel synthesis that may be considered to be a library of imino (aza) sugars (glycomimetics) and/or dihydroxyprolyl peptides (peptidomimetics). The utility of generating such a library was illustrated by scr...
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A new and improved protocol for the synthesis, in good to excellent yields, of acridine-1,8(2H,5H)-diones is described, involving a one-pot, three component reaction of dimedone, arylglyoxals, and ammonium acetate in water under microwave irradiation.
متن کاملMicrowave-Assisted Three Component Cyclocondensation Reaction: A Facile Synthesis of Highly Functionalized Cyclohexene Derivatives
Microwave-assisted three component cyclocondensation reactions of aldehydes, amides and dienophiles in the presence of acetic anhydride and para-toluenesulfonic acid as a catalyst to afford the highly substituted cyclohexene derivatives, in relatively good yields after several minutes are reported.
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ژورنال
عنوان ژورنال: Angewandte Chemie International Edition
سال: 2008
ISSN: 1433-7851
DOI: 10.1002/anie.200890147